Dermatofibrosarcoma Protuberans; Case Report of a Rare Tumor of the Breast

نویسندگان

  • Asieh Olfatbakhsh Breast Diseases Department, Breast Cancer Research Center, ACECR , Tehran, Iran
  • Esmat Alsadat Hashemi Breast Diseases Department, Breast Cancer Research Center, ACECR , Tehran, Iran
  • Mahsa Keshavarz-Fathi Tehran University of Medical Sciences, Tehran, Iran and Cancer Immunology Project (CIP), Universal Scientific Education and Research Network (USERN), Tehran, Iran
  • Parandis Hoseinpour University of Ludwig Maximilian, Munich, Germany
  • Parisa Hoseinpour Breast Diseases Department, Breast Cancer Research Center, ACECR , Tehran, Iran
  • Toktam Beheshtian Breast Diseases Department, Breast Cancer Research Center, ACECR , Tehran, Iran
چکیده مقاله:

Introduction: Dermatofibrosarcoma protuberans (DFSP) is an intermediate and slowgrowing sarcoma, developing most commonly in the trunk and extremities and rarely in the breast. It may be recurrent, but metastasis is not common. Excisional surgery with enough resection margins decreases the recurrence rate much more. Case Presentation: An 18-year-old woman presented with posttraumatic bruising of the right axilla near her breast which had been converted to a nodular mass. A well-defined firm mass, fixed to the dermis, palpable with mild tenderness, was present. Ultrasound (US) revealed a cyst with thickened wall, internal echo septa and high vascularity. The findings were suggestive of a complex cyst or infected epidermal inclusion cyst (EIC). Pathological investigation revealed uniform spindle cells in a storiform arrangement. In immunohistochemistry (IHC), tumoral cells showed reactivity for CD34 and the diagnosis of DFSP was made. Conclusion: Various breast lesions including cysts as well as benign and malignant masses may show similar appearance in imaging studies, which makes clear the crucial role of the pathological and immunohistochemical investigations to confirm a definite diagnosis.

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عنوان ژورنال

دوره 1  شماره None

صفحات  26- 28

تاریخ انتشار 2017-01

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